The 18th ACM SIGPLAN/SIGOPS International Conference on Virtual Execution Environments (VEE’22) brings together researchers in the broad area of virtualization. This area includes topics such as compiler-based virtual machines (JVM, CLR, LLVM, etc.), operating system abstractions for virtualization (processes, containers), hardware accelerated system virtual machines (paravirtualization, hypervisors), translators, machine emulators, and simulators. Although these layers have different design and implementation techniques, the fundamental challenges and insights tend to be similar.